Detection of Zika Virus and Human Papilloma Virus in Cervical Cytology Samples using Two Real Time PCR Based Techniques in Ecuadorian Women diagnosed with ASCUS
Vol. 37 (2018), ZIKA-ASSOCIATED HEALTH PROBLEMS - Other Health Problems
Vol. 37 (2018)

Detection of Zika Virus and Human Papilloma Virus in Cervical Cytology Samples using Two Real Time PCR Based Techniques in Ecuadorian Women diagnosed with ASCUS

ZIKA-ASSOCIATED HEALTH PROBLEMS - Other Health Problems
Published 2018-12-19
  • Pool Tobar+−
  • Marcela Vega
  • Cathy Ordoñez
  • Lisette Rivera
  • José Landivar
  • Héctor Zambrano
Pool Tobar
Universidad Catolica de Santiago de Guayaquil. Luis Vernaza Hospital
Marcela Vega
Cathy Ordoñez
Lisette Rivera
José Landivar
Héctor Zambrano
PDF

Keywords

ZIKA
ASCUS
RT-PCR

How to Cite

Tobar, P., Vega, M., Ordoñez, C., Rivera, L., Landivar, J., & Zambrano, H. (2018). Detection of Zika Virus and Human Papilloma Virus in Cervical Cytology Samples using Two Real Time PCR Based Techniques in Ecuadorian Women diagnosed with ASCUS. Puerto Rico Health Sciences Journal, 37, S96-S98. Retrieved from https://prhsj.rcm.upr.edu/index.php/prhsj/article/view/1808
ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver

Download Citation

Endnote/Zotero/Mendeley (RIS) BibTeX

Abstract

Objective: Atypical Squamous Cells of Undetermined Significance(ASCUS) is the most reported result on pap smears. It is most commonly related to Human Papillomavirus (HPV) infections. However, other pathogens (EBV, Chlamydia) have been reported on cervical samples with abnormal results. Zika virus(ZIKV) has been found to induce cellular abnormalities on different tissues and its presence has been identified on genital secretions. Methods: Two real-time PCR has been made on cervical samples from the gynecological service of a third level hospital on Guayaquil-Ecuador. This work was part of a bigger study of ZIKV presence on different body fluids. Results: From 89 samples obtained, 19 received an ASCUS result. From these 5 were positive for ZIKV and 5 were positive for HPV, there were no co infections. Conclusion: Given the presence of ZIKV RNA and the absence of HPV DNA on cervical samples diagnosed as ASCUS, it might be plausible that ZIKV could be a triggering factor for the induction of cellular changes observed on these cells.
PDF
Authors who publish with this journal agree to the following terms: a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).