Gastric MALT Lymphoma with Biclonal Gammopathy and Bone Marrow Involvement Mimicking Multiple Myeloma
Vol. 39 No. 3 (2020), Case Report
Vol. 39 No. 3 (2020)

Gastric MALT Lymphoma with Biclonal Gammopathy and Bone Marrow Involvement Mimicking Multiple Myeloma

Case Report
Published 2020-09-17
William Cáceres-Perkins
UPR School of Medicine Hematology-Oncology and Pathology sections VA Caribbean Healthcare system 10 Calle Casia, San Juan , Puerto Rico 00921
Fernando Cabanillas
Auxilio Mutuo Cancer Center, San Juan, Puerto Rico; Hematology-Oncology Section, University of Puerto Rico School of Medicine, San Juan, Puerto Rico; Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.
Glorivette San Vicente
Hematology-Oncology and Pathology sections VA Caribbean Healthcare system 10 Calle Casia, San Juan , Puerto Rico 00921
Carlos Rivera-Franceschini
Hematology-Oncology and Pathology sections VA Caribbean Healthcare system 10 Calle Casia, San Juan , Puerto Rico 00921
Elías Sobrino-Najul
Hematology-Oncology and Pathology sections VA Caribbean Healthcare system 10 Calle Casia, San Juan , Puerto Rico 00921
Laura I. Vega-Vázquez
Hematology-Oncology and Pathology sections VA Caribbean Healthcare system 10 Calle Casia, San Juan , Puerto Rico 00921
Daniel Conde-Sterling
Hematology-Oncology and Pathology sections VA Caribbean Healthcare system 10 Calle Casia, San Juan , Puerto Rico 00921
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Keywords

Marginal zone B-cell lymphoma
Biclonal gammopathy
Bone marrow

How to Cite

Cáceres-Perkins, W., Cabanillas, F., San Vicente, G., Rivera-Franceschini, C., Sobrino-Najul, E., Vega-Vázquez, L. I., & Conde-Sterling, D. (2020). Gastric MALT Lymphoma with Biclonal Gammopathy and Bone Marrow Involvement Mimicking Multiple Myeloma. Puerto Rico Health Sciences Journal, 39(3), 275–277. Retrieved from https://prhsj.rcm.upr.edu/index.php/prhsj/article/view/2041
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Abstract

Mucosa-associated lymphoid tissue (MALT) lymphomas are B-cell neoplasms that commonly affect the gastrointestinal (GI) tract, usually the stomach. In most cases, extranodal marginal zone lymphoma (ENMZL) is an indolent disease. Bone marrow involvement is common with MALT lymphoma accompanied by paraproteinemia; such involvement impels disease progression. Here, we present the case of an 82-year-old Hispanic patient with long-standing ENMZL in whom the gastric site responded to antibiotic treatment and Helicobacter pylori eradication, but the disease progressed over the years, with a biclonal gammopathy and bone marrow involvement with marked plasmacytic differentiation. In view of this, we suggest the routine evaluation of paraprotein in patients with ENMZL.
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