How to Cite
Delgado, E., Hernández-Cott, P. L., Stewart, B., Collins, M., & De Vizio, W. (2009). Tooth-whitening efficacy of custom tray-delivered 9% hydrogen peroxide and 20% carbamide peroxide during daytime use: A 14-day clinical trial. Puerto Rico Health Sciences Journal, 26(4). Retrieved from https://prhsj.rcm.upr.edu/index.php/prhsj/article/view/225
Abstract
Objective: The purpose of this 14-day parallel, double blind clinical trial was to evaluate the tooth whitening efficacy of a 9% hydrogen peroxide gel (Colgate Visible White) relative to a 20% carbamide peroxide gel (Opalescence) positive control. Methods: Forty-six consenting adults were randomly assigned to use one of the two products. All participants had 6 unrestored maxillary anterior teeth averaging a shade ranking score of 9 (A3) in the Vitapan Classical Shade Guide scale of 1 through 16 (lightest to darkest). Tooth whitening consisted of at-home 30- minute daily self-applications of the assigned product after brushing with a non-bleaching dentifrice. One of two calibrated examiners performed the baseline, 5- day, 7-day, and 14-day tooth shade evaluations for a given participant, utilizing the same Vita guide under unmodified color-corrected lighting conditions. Thirtyseven participants made all visits. Bleaching efficacy was measured with respect to mean shift (reduction from baseline) in rank scores of the maxillary anterior teeth, in which baseline rank scores functioned as covariables. Results: Both treatment groups exhibited statistically significant mean shade rank score improvements from baseline after 5,7, and 14 days at 3.14, 3.70 and 4.68 for Colgate Visible White and 1.60, 2.52 and 3.85 for Opalescence. Conclusions: Between-group comparison shows that while Colgate Visible White (9% hydrogen peroxide) provides a statistically significant tooth whitening improvement over Opalescence (20% carbamide peroxide) after 5 days of self-application, both products have a similar whitening effect after 7 and 14 days.
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