Keywords
localized scleroderma
morphea
nephrogenic systemic fibrosis
gadolinium
kidney disease
morphea
nephrogenic systemic fibrosis
gadolinium
kidney disease
How to Cite
Rodriguez-Baisi, K. E., Santaliz-Ruiz IV, L. E., Diaz-Martinez, A. J., Pagan, A. D., Sánchez, N. P., & Villa, J. (2022). An Unusual Case of Deep Localized Scleroderma in a Patient with Chronic Kidney Disease. Puerto Rico Health Sciences Journal, 41(1), 45–48. Retrieved from https://prhsj.rcm.upr.edu/index.php/prhsj/article/view/2466
Abstract
Localized scleroderma (LS) is a rare fibrosing disorder of skin and underlying tissues. Although it can affect all races, it has a higher prevalence in whites. Deep LS is the least common among seven LS variants, representing less than 5% of cases, and typically affects areas of pressure such as the hips and waist. We report a unique clinical case of bilateral lower extremity deep LS in a 51-year-old Puerto Rican woman with chronic kidney disease (CKD). In patients with CKD, it is important to distinguish LS from nephrogenic systemic fibrosis (NSF). Both can present with skin fibrosis and contractures over joints yet have significantly differing treatment approaches and prognosis. Our case report is unique due to the patient’s Puerto Rican ethnicity, CKD history, and isolated anterior lower extremity involvement. In this report, we highlight key clinical and histopathological findings of LS, and how they differ from that of NSF.
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