Acute Fatty Liver of Pregnancy: Incidence and Clinical Evolution in Toluca, Mexico

Abstract

Objective: The objective of this study was to determine the incidence and evolution of patients with acute fatty liver of pregnancy (AFLP) over a period of 18 years in the city of Toluca, Mexico. Methods: This was a descriptive and retrospective study of eighteen years. All women with AFLP confirmed by biopsy were included and the incidence, laboratory test values and complications were registered. Results: AFLP incidence was of 1 case for every 8,451 deliveries. The main complications were bleeding, infections and neurological compromise. The mortality was of 33.33%. Conclusion: It can be concluded that AFLP has a slightly lower incidence in Mexico than that reported in other countries but with a higher survival. This condition deserves a multidisciplinary team to improve the survival rate.