Anaplastic T-cell Lymphoma Presenting as Fatal Acute Liver Failure

Luis Angel Armstrong, Doris H. Toro, Jaime Martínez-Souss, Betty Chinea, Daniel Conde-Sterling


Acute liver failure (ALF) is an uncommon manifestation of liver disease and constitutes a medical emergency for which early identification is necessary. Hepatic involvement by hematologic malignancies although frequent, rarely causes severe hepatic dysfunction. Even more, acute hepatic failure as the first manifestation of a hematologic malignancy is extremely uncommon, although some cases have been reported in the literature. We describe the case of a 61 y/o puertorrican veteran who developed acute hepatic failure secondary to massive infiltration of the liver by a recurrent non-Hodgkin’s lymphoma.

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