Abstract
The World Health Organization estimates the world prevalence of viral hepatitis C at 3%. The advent of therapeutic regimens for viral hepatitis has made the liver biopsy a routine specimen in the surgical pathology laboratory. The clinician will need to know the degree and type of necroinflammatory activity and the presence and level of fibrosis, before making the decision to start therapy. The biopsy is essential in determining the nature and extent of hepatic injury, the degree of inflammation, the type of inflammatory reaction, the distribution of fibrosis and the presence of other findings affecting the patient’s prognosis. A scoring system is essential in the therapeutic trials for treatment of viral hepatitis and can be helpful in making therapeutic decisions. The aim of this article is to summarize the terminology, histologic findings, the available and more commonly used scoring systems and the surgical report of chronic viral hepatitis C.
Authors who publish with this journal agree to the following terms:
a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).