Metabolic Correction: A Functional Biochemical Mechanism against Disease • Part 2: Mechanisms and Benefits

Jorge R. Miranda-Massari, Michael J. González, Jorge Duconge, Myriam Z. Allende-Vigo, Francisco J. Jiménez-Ramírez, Steve Hickey, Alex Vázquez, Miguel J. Berdiel, Kenneth Cintrón, José R. Rodríguez-Gómez


A healthy physiology depends on a plethora of complex interdependent biochemical reactions. In order for these reactions to occur suitably, the enzymes and cofactors that regulate their flow must be present in the proper balance. The term metabolic correction is used to describe a biochemical–physiological process that improves cellular biochemistry as a means to an individual’s achieving metabolic or physiological optimization. Part 2 discusses how metabolic correction, through the increase of cofactors, can supply unmet enzyme needs and compensate for nutritional deficiencies induced by improper nutritional intake or by the increased demand for nutrients caused by genetics, health conditions, medications, or physical or environmental stressors. Nutrient insufficiencies are causing an increase in morbidity and mortality, at great cost to our society. In summary, metabolic correction improves enzymatic function and satisfies the increasing demand for nutrients. Metabolic correction can have a significant impact on the reduction of morbidity and mortality and their financial cost to our society and contribute to improving health and wellbeing.

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