Characteristics, Upon Presentation, of a Cohort of Patients with Vogt-Koyanagi-Harada Disease in Puerto Rico

Viviana Barquet, Eduardo Rodríguez, Andres Fantauzzi, Jan C. Ortíz, Jan P. Ulloa-Padilla, Mariam S. Vilá-Delgado, Carlos J. Fernández, Juan C. Almodóvar, Carmen Santos, Armando L. Oliver


Objective: To describe the clinical features, upon initial presentation, of a cohort of patients with Vogt-Koyanagi-Harada (VKH) disease who live in Puerto Rico. Methods: A retrospective medical record review of patients with VKH was performed. The demographic and clinical characteristics were analyzed. Results: Twenty-two patients who met the diagnostic criteria for VKH were identified and included in the analysis. The median age at presentation was 41 years; 68.2% were female, and all patients were Hispanics. Bilateral disease was present in 90.9% of patients, and 59.1% of patients were categorized as having probable VKH. A headache was reported in 54.5% of patients and was the most common complaint at the time of presentation; the second most common complaint was tinnitus, which was present in 22.7% of patients. Vitiligo, alopecia, and meningismus were each preset in 9.1% of patients while hearing loss and aseptic meningitis were each reported in 4.5% of patients. Seventy-seven percent of patients had either topical or systemic corticosteroid use prior to the initial encounter. Conclusions: Our study suggests that in Puerto Rico, patients with Vogt-Koyanagi-Harada disease may have a distinctive prevalence of characteristics at the presentation when compared to other ethnic groups, including other Hispanic cohorts.


Vogt-Koyanagi-Harada, panuveitis, Puerto Rico, Hispanics

Full Text:


Published by the University of Puerto Rico Medical Sciences Campus
Founded in 1982